DSpace Collection:
https://hdl.handle.net/20.500.12394/7780
2024-03-29T09:23:03ZScientific Writing Series: Systematic Review
https://hdl.handle.net/20.500.12394/10332
Title: Scientific Writing Series: Systematic Review
Authors: Quispe, Antonio M.; Hinojosa-Ticona, Yessica; Miranda, Herbert A.; Sedano, Claudia A.
Abstract: Introducción: La revisión sistemática es la evaluación comprehensiva, reproducible, crítica y explícita de la mejor evidencia disponible en respuesta a una pregunta de investigación específica. Para conseguir ello las revisiones sistemáticas deben cubrir como mínimo los siguientes siete pasos: i) una pregunta de investigación específica y estructurada usando la técnica PICO; ii) criterios de elegibilidad de las evidencias; iii) una estrategia de búsqueda clara y reproducible; iv) selección de las evidencias y extracción de datos; v) análisis de sesgos; vi) síntesis de resultados; y, vii) publicación. Si los datos son suficientes y homogéneos es factible incluir en las síntesis de resultados el metanálisis de los mismos. De esta manera las revisiones sistemáticas y metanálisis pueden generar conocimiento nuevo y fundamental para la toma de decisiones en el área clínica y en otras áreas2021-01-01T00:00:00ZFactors associated with high-grade erectile dysfunction (ED) in tuberculosis patients from a hospital in Lima, Peru
https://hdl.handle.net/20.500.12394/10284
Title: Factors associated with high-grade erectile dysfunction (ED) in tuberculosis patients from a hospital in Lima, Peru
Authors: Reyes-Paredes, Marjorie; Valladares-Garrido, Mario Josué; Ichiro Peralta, Christopher; Dominguez-Troncos, Helena; Grandez-Urbina, Antonio
Abstract: Objetivo: Determinar la prevalencia y factores asociados a DE (disfunción eréctil) alto grado en Lima, Perú.
Material y métodos: Estudio transversal analítico en pacientes tuberculosos atendidos en consultorio externo.2021-01-01T00:00:00ZUse of medicinal plants for COVID-19 prevention and respiratory symptom treatment during the pandemic in Cusco, Peru: A cross-sectional survey
https://hdl.handle.net/20.500.12394/10270
Title: Use of medicinal plants for COVID-19 prevention and respiratory symptom treatment during the pandemic in Cusco, Peru: A cross-sectional survey
Authors: Villena-TejadaI, Magaly; Vera-Ferchau, Ingrid; Cardona-Rivero, Anahı ́; Zamalloa- Cornejo, Rina; Quispe-Florez, Maritza; Frisancho-Triveño, Zany; Abarca- Meléndez, Rosario C.; Alvarez-Sucari, Susan G.; Mejia, Christian R.; Yañez, Jaime A.
Abstract: Background
The burden of the COVID-19 pandemic in Peru has led to people seeking alternative treat-
ments as preventives and treatment options such as medicinal plants. This study aimed to
assess factors associated with the use of medicinal plants as preventive or treatment of
respiratory symptom related to COVID-19 during the pandemic in Cusco, Peru.
Method
A web-based cross-sectional study was conducted on general public (20- to 70-year-old)
from August 31 to September 20, 2020. Data were collected using a structured question-
naire via Google Forms, it consisted of an 11-item questionnaire that was developed and
validated by expert judgment using Aiken’s V (Aiken’s V > 0.9). Both descriptive statistics
and bivariate followed by multivariable logistic regression analyses were conducted to
assess factors associated with the use of medicinal plants for COVID-19 prevention and
respiratory symptom treatment during the pandemic. Prevalence ratios (PR) with 95% Con-
fidence Interval (CI), and a P-value of 0.05 was used to determine statistical significance.
Results
A total of 1,747 respondents participated in the study, 80.2% reported that they used medici-
nal plants as preventives, while 71% reported that they used them to treat respiratory symp-
toms. At least, 24% of respondents used medicinal plants when presenting with two or more
respiratory symptoms, while at least 11% used plants for malaise. For treatment or prevention, the multivariate analysis showed that most respondents used eucalyptus (p <
0.001 for both), ginger (p < 0.022 for both), spiked pepper (p < 0.003 for both), garlic (p =
0.023 for prevention), and chamomile (p = 0.011 for treatment). The respondents with
COVID-19 (p < 0.001), at older ages (p = 0.046), and with a family member or friend who
had COVID-19 (p < 0.001) used more plants for prevention. However, the respondents with
technical or higher education used less plants for treatment (p < 0.001).
Conclusion
There was a significant use of medicinal plants for both prevention and treatment, which
was associated with several population characteristics and whether respondents had
COVID-19.2021-01-01T00:00:00ZHigh altitude and cancer: An old controversy
https://hdl.handle.net/20.500.12394/10102
Title: High altitude and cancer: An old controversy
Authors: Calderon Gerstein, Walter S.; Torres Samaniego, Gabriela
Abstract: Ecological studies have found that individuals that live at high altitude regions and in places where ultraviolet
radiation is maximal, have lower rates of different types of cancer. However, there is evidence that in these same
regions, genetic mutations that are prooncogenic, develop, as they are needed to increase human adaptability to
hypoxic environments. Debate has arisen between researchers who consider high altitude environments as
suitable for human longevity because of its protective effects against malignancies, and scientists that have re-
ported an increased incidence of different type of cancers in these same regions. Evidence is presented that
altitude is related to the development of genetic alterations in micro RNAs, p53 protein, lymphocyte activity,
decrease in Fas Ligand and other proapoptotic molecules, as well as increase in prometastatic VGEF an HIF.
Notwithstanding, higher vitamin D and ultraviolet B levels, and a better metabolic profile, taken together with
lower pollution levels hves been related to lower incidence and mortality rates from malignancies in a series of
epidemiological studies.2021-01-01T00:00:00Z