Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12394/9940
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dc.contributor.authorCalderón-Gerstein, Walteres_ES
dc.contributor.authorBruno-Huamán, Astrides_ES
dc.contributor.authorDamián-Mucha, Milagroses_ES
dc.contributor.authorHuayllani-Flores, Lizetes_ES
dc.date.accessioned2021-08-20T21:19:41Z-
dc.date.available2021-08-20T21:19:41Z-
dc.date.issued2021-
dc.identifier.citationCalderón, W., Bruno, A., Damián, M., Huayllani, L., (2021). Predictive capacity of the brain natriuretic peptide in the screening of heart failure in a high altitude population. Respiratory Physiology and Neurobiology, 289(1), [2]. https://doi.org/10.1016/j.resp.2021.103654es_ES
dc.identifier.urihttps://hdl.handle.net/20.500.12394/9940-
dc.descriptionBackground Heart failure (HF) is growing in importance as a significant cause of disease and mortality. When It is suspected, it can be ruled out if BNP values are below 100 pg/mL. Diagnostic certainty can be obtained if echocardiogram shows reduced ejection fraction, diastolic dysfunction or right-sided heart disease. Physiological changes at high altitude are known to affect BNP values. This study pretends to evaluate BNP values when used for HF diagnosis in Huancayo, Perú, a high altitude population located at 3,250 m above sea level. Methods This is a cross-sectional, diagnostic test type study. A total of 83 medical charts of patients with suspected HF, admitted to the Emergency Room and Internal Medicine Service of Ramiro Prialé Prialé National Hospital, were reviewed. Data processing was performed with SPSS program for Windows version 21.0. Pearson's Chi Square test was used for categorical variables analysis and ANOVA for continuos variables. P values under 0.05 were considered significant. Results and conclusions Medium age was 74 years. Patient’s characteristics that were associated with confirmed HF and high BNP levels were the following: presence of fatigue, night cough, elevated heart rate, shortness of breath, history of lung fibrosis and decreased oxygen arterial saturation (p < 0.05) Pulmonary hypertension, mitral and tricuspid regurgitation, and cor pulmonale were also associated with higher BNP levels. Most subjects had BNP values >100 pg/mL, with low specificity for HF diagnosis (11.5 %). Individuals without heart failure had mean BNP values above 300 pg/mL; while individuals with cor pulmonale had a mean of 975 pg/mL. BNP values were high in patients with or without HF. A cut-off point of ≥130pg/mL is proposed to increase specificity. The predictive capacity of BNP for HF identification at this high altitude population is low because of a high number of false positive results.es_ES
dc.formatapplication/pdfes_ES
dc.format.extentp. [2]es_ES
dc.language.isoenges_ES
dc.publisherUniversidad Continentales_ES
dc.relationhttps://www.sciencedirect.com/science/article/abs/pii/S1569904821000392?via%3Dihubes_ES
dc.rightsinfo:eu-repo/semantics/restrictedAccesses_ES
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_ES
dc.subjectPéptido natriurético cerebrales_ES
dc.subjectInsuficiencia cardiacaes_ES
dc.subjectDiagnósticoes_ES
dc.titlePredictive capacity of the brain natriuretic peptide in the screening of heart failure in a high altitude populationes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.description.notePara acceder al artículo de su interés, puede solicitarlo a bibliotecariovirtual@continental.edu.pe. Por favor, comunicarse con su correo institucional.es_ES
dc.rights.accessRightsRestringidoes_ES
dc.identifier.journalRespiratory Physiology and Neurobiologyes_ES
dc.identifier.doihttps://doi.org/10.1016/j.resp.2021.103654es_ES
dc.subject.ocdehttp://purl.org/pe-repo/ocde/ford#1.02.02es_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
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