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Repositorio Institucional Continental

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Title: CrpP, a passenger or a hidden stowaway in the Pseudomonas aeruginosa genome?
Alternative Titles: ¿CrpP, un pasajero o un polizón oculto en el genoma de Pseudomonas aeruginosa?
Authors: Ruiz, Joaquim
Keywords: Quinolonas
Publisher: Universidad Continental
Issue Date: 23-Jul-2019
Date available: 17-Jul-2020
Creation date: 2020
Bibliographic citation: Ruiz, J. (2019). CrpP, a passenger or a hidden stowaway in the Pseudomonas aeruginosa genome?. Journal of Antimicrobial Chemotherapy, 1(1), 3397-3399. https://doi. 10.1093/jac/dkz316
DOI: 10.1093/jac/dkz316
Abstract: CrpP, an enzyme able to phosphorylate ciprofloxacin, was described in 2018 as encoded within the plasmid pUM505 of Pseudomonas aeruginosa; on cloning crpP in a J53 background, the MIC of ciprofloxacin rose from 0.008 to 0.06 mg/L.1 Thereafter, crpP-like genes have been reported in Escherichia coli and Klebsiella pneumoniae.2 At present, the prevalence of CrpP and its geographical dissemination, presence within mobile genetic elements and potential ancestral origins remain to be determined. In this scenario, the advances in genomic sequencing may provide valuable information about some of these questions. Thus, this study aimed to determine the presence...
Notes: El texto completo de este trabajo no está disponible en el Repositorio Institucional - Continental por restricciones de la casa editorial donde ha sido publicado.
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metadata.dc.format.extent: p. 3397-3399
Access: Restringido
Source: Universidad Continental
Repositorio Institucional - Continental
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